STROMAL CELLS IN THE TUMOR MICROENVIRONMENT: ACCOMPLICES OF TUMOR PROGRESSION?

Abstract The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.These three types of cells establish complex signals in the body and further influence tumor genesis, development, metastasis and

Abstract Background Orbital emphysema and pneumocephalus rarely occur without associated skull fractures.Over the past decades, a few case reports have documented compressed air injuries as a rare cause of orbital emphysema and pneumocephalus in the absence of concomitant skull fractures leading to various injuries.Case presentation We illustrate h